Software and Model
C.Origami
A multimodal deep learning model that predicts cell-type-specific chromatin organization from DNA sequence, chromatin accessibility, and CTCF binding (Tan et al. Nat. Biotechnol. 2023).
Chromnitron
A multimodal foundation model that learns the rules of protein–DNA interaction by integrating DNA sequence, chromatin accessibility, and protein amino acid sequence (Tan et al. bioRxiv 2025).
CANVAS
A self-supervised representation learning framework for analyzing highly multiplexed imaging data (Tan et al. Nat. Biomed. Eng. 2025).